Proof Pudding supported by Medium Chain Triglycerides (MCTs)

MCTs are a type of fat found in coconut oil and dairy products that are rapidly absorbed and metabolized by the liver into ketones- an alternative energy source for the brain. Ketones can cross the blood-brain barrier and may provide cognitive benefits, especially in conditions where glucose metabolism is impaired, such as Alzheimer's disease.

Research has shown that MCTs supplementation may improve memory and attention in individuals with mild cognitive impairment (Cunnane et al., 2020; Avgerinos et al., 2020; Fortier et al., 2021), and can improve executive function (making plans, solving problems, etc.) in healthy elderly subjects (Yomogida et al., 2021).

References:

• Avgerinos K et al. (2020). Medium Chain Triglycerides induce mild ketosis and may improve cognition in Alzheimer's disease. A systematic review and meta-analysis of human studies. Ageing Res. Rev.

• Fortier M et al. (2021). A ketogenic drink improves cognition in mild cognitive impairment: Results of a 6-month RCT. Alzheimer's Dement.

• Cunnane SC et al. (2020). Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing. Nat Rev Drug Discov.

• Yomogida Y et al. (2021). An fMRI Investigation into the Effects of Ketogenic Medium-Chain Triglycerides on Cognitive Function in Elderly Adults: A Pilot Study. Nutrients.